August 2023

Bovine Respiratory Panel Summary Results for 2022

By Dr. Gregg Hanzlicek

The graph below highlights the 2022 results from the KSVDL Bovine Respiratory Panel submissions.

Most of the samples (74.3%) were from beef production systems originating from 26 U.S. states. There were 486 total submissions (each submission included samples from 1 to 16 animals.) Overall, 4,794 individual PCRs were completed on upper respiratory samples and 5,173 on lower respiratory samples.

Upper respiratory samples included nasal and deep pharyngeal swabs, and lower respiratory samples included lung tissue, lung swabs, transtracheal washes, and bronchioalveolar lavages.

PCR positives

A reminder: PCR positive results for samples collected (both upper and lower) from animals that were vaccinated within the previous 10-14 days may represent vaccine virus, and not field exposure.

KSVDL can genetically analyze (gene sequence) the virus strain contained in a positive sample and genetically compare it to the vaccine strains in our library that includes all available commercial modified vaccine strains for IBR, BVD, BRSV, Corona, and Rota viruses.

The analysis results will not only determine if the virus is a vaccine or field strain, but it will also provide practitioners information that can help them select the most effective vaccine.

For example: lung samples from two calves were found to contain a BVD field strain. The analysis suggested that Vaccine A or B would be the best selection against this field strain and little cross protection could be expected from Vaccines C and D.

*The actual KSVDL report will provide the names of the vaccines.

% Similarity Between Vaccine and Sample Strain

ML Vaccines Containing BVD

Calf ID Vaccine A* Vaccine B* Vaccine C* Vaccine D*
Y58: 90.8 90.8 29.3 35.3
Y77: 95.7 95.5 31.6 36.2


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